CLUSTALWPROF
CLUSTALWPROF is a specialized function of CLUSTALW. It is used to add either individual sequences to an existing alignment, or it can be used to merge two existing alignments. for global multiple alignment of DNA and protein sequences. Guide trees from these alignments can be used. The program has some adjustable parameters with reasonable defaults.
INPUT = dna sequence alignments (aka profiles); protein sequence files (aka profiles) guide trees in newick format.
Manual: http://www.ebi.ac.uk/2can/tutorials/nucleotide/clustalw1.html
Test input profile1: clustal_profile_test_in1.aln
Test input profile2: clustal_profile_test_in2.aln
Test output file: clustal_profile_test_out1.aln